[HTML][HTML] Genetic variants in TKT and DERA in the nicotinamide adenine dinucleotide phosphate pathway predict melanoma survival
Background Cutaneous melanoma (CM) is the most lethal type of skin cancers.
Nicotinamide adenine dinucleotide phosphate (NADPH) plays an important role in anabolic
reactions and tumorigenesis, but many genes are involved in the NADPH system. Methods
We used 10,912 single-nucleotide polymorphisms (SNPs)(2018 genotyped and 8894
imputed) in 134 NADPH-related genes from a genome-wide association study (GWAS) of
858 patients from The University of Texas MD Anderson Cancer Center (MDACC) in a single …
Nicotinamide adenine dinucleotide phosphate (NADPH) plays an important role in anabolic
reactions and tumorigenesis, but many genes are involved in the NADPH system. Methods
We used 10,912 single-nucleotide polymorphisms (SNPs)(2018 genotyped and 8894
imputed) in 134 NADPH-related genes from a genome-wide association study (GWAS) of
858 patients from The University of Texas MD Anderson Cancer Center (MDACC) in a single …
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